Senior Scientist II - Process Chemistry & Radiochemistry
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North Chicago, IL
- Research & Development
- Full-time
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013, following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader, to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 50,000 people worldwide and markets medicines in more than 170 countries.
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.
AbbVie Process Chemistry Department is seeking a Senior Scientist II. This role will be in the Radiochemistry group, which specializes in the synthesis of radiolabeled APIs using long half-life, beta-emitting isotopes. These compounds support screening assays and metabolism studies that are critical to advancing drug development. This role requires expertise in both process chemistry and radiochemistry.
Key responsibilities:
· The candidate will contribute to, and may lead, project teams focused on process development and characterization of radiolabeled small molecules, peptides, antibody drug conjugates and other emerging modalities.
o Develop and optimize radiolabeling strategies for peptides and related compounds.
o Collaborate across functions to support the purification, isolation, and formulation of radiolabeled drug substances, peptides and other modalities.
o Set project strategies and provide leadership in a cross-functional team environment.
· This position will require experience with cGMP activities related to the preparation of radiolabeled API to comply with corporate and regulatory standards.
· Demonstrated expertise in transition metal-catalyzed cross-coupling reactions, reaction development, and hydrogen isotope exchange. Proven ability to overcome key project challenges by applying strong technical knowledge and data-driven problem-solving.
· Contribute to the strategic direction of the group by identifying new development opportunities and incorporating external scientific advancements in collaboration with peers, subordinates, and senior leadership. Provide mentorship and guidance to staff in addressing both strategic challenges and experimental troubleshooting.
· Proactively stay current with scientific literature and incorporate relevant insights into ongoing projects and broader program strategy.
· Demonstrated flexibility to support Process Chemistry pipeline projects and Radiochemistry group labeling deliveries as capacity demands require.
· This role may include managing direct reports.
Minimum Qualifications:
- A PhD in organic chemistry and 4+ years of experience OR MS in organic chemistry and 10+ years of experience.
- Experience with the use and handling of radioactive materials (Beta emitters).
- Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations on cross-functional process development teams.
- Effective writer and communicator of research or other regulatory materials required.
Key AbbVie Competencies:
- Interacts well with diverse groups within function and maintain strong working relationships with internal and external collaborators to enable higher performance.
- Learns fast, grasps the "essence" and can change course quickly where indicated
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Level and compensation will be commensurate with experience.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
This job is eligible to participate in our long-term incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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