Scientist l, Biological Research
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Irvine, CA
- Research & Development
- On-Site
- Full-time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
The Toxin Innovation Group is seeking a highly motivated Scientist I to contribute to the design, execution, and communication of novel research within a highly collaborative neurotoxin discovery and innovation program. The successful candidate will work on a variety of cell-based assays to evaluate protein-based therapeutics and contribute to their pharmacological characterization. Expertise in maintaining induced pluripotent stem cell (iPSC) cultures and executing complex cell-based assays is required. While taking personal responsibility for the success of assigned tasks and projects, the successful candidate will collaborate extensively with other scientists.
This position requires work with select agents and toxins (i.e., Biosafety Level 2 laboratories). Access to and use of select agents is regulated by federal policies; therefore, the candidate must conduct all work activities in compliance with AbbVie internal requirements and applicable regulatory requirements.
Key responsibilities:
Culture cells in a sterile environment, including the expansion, differentiation, and maturation of human iPSC-derived neurons
Independently design and execute in vitro pharmacological studies; implement or innovate new experimental protocols as needed
Perform in-depth data analysis, draw conclusions, and present findings to multidisciplinary teams
Demonstrate critical thinking to troubleshoot and provide creative solutions to experimental challenges
Collaborate with cross-functional team members to achieve organizational goals, ensuring excellence in execution and effective workload prioritization
JOB QUALIFICATIONS (MINIMUM REQUIREMENTS):
Highly motivated, hands-on experimentalist who thrives in a collaborative, multidisciplinary environment
Demonstrates flexibility and a commitment to scientific excellence
Possesses strong interpersonal and organizational skills, as well as creative thinking ability
Able to perform experiments independently and work effectively in a team environment
Interprets results and draws conclusions from multi-step experiments; notes significant deviations, uses scientific literature to suggest, design, and pursue relevant experiments
Demonstrates meticulous attention to detail and diligence in record keeping
Education and Experience
Minimum of a bachelor’s degree in a biological science field with 5 years of experience in an academic or industry laboratory setting
Expertise in aseptic techniques, including maintaining iPSC cell cultures is required
Experience in cell transfection/transduction is preferred
Expertise in executing enzyme-linked immunosorbent assays (ELISA), complex cell-based assays, and western blotting is required
Experience with immunohistochemistry, microscopy techniques, and/or flow cytometry is preferred
Computer skills: working knowledge of MS Office (Excel, Word, PowerPoint) is required
Knowledge of graphing software (e.g., GraphPad Prism) and a basic understanding of statistical analyses are preferred
Strong writing and communication skills
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
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Pay Range: $
75000 - 142500 USD
Where We Work
Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.