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Scientist l, Biological Research

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Irvine, CA

  1. Research & Development
  2. On-Site
  1. Full-time
R00146076

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, FacebookInstagramX and YouTube.


Job Description

The Toxin Innovation Group is seeking a highly motivated Scientist I to contribute to the design, execution, and communication of novel research within a highly collaborative neurotoxin discovery and innovation program. The successful candidate will work on a variety of cell-based assays to evaluate protein-based therapeutics and contribute to their pharmacological characterization. Expertise in maintaining induced pluripotent stem cell (iPSC) cultures and executing complex cell-based assays is required. While taking personal responsibility for the success of assigned tasks and projects, the successful candidate will collaborate extensively with other scientists. 

This position requires work with select agents and toxins (i.e., Biosafety Level 2 laboratories). Access to and use of select agents is regulated by federal policies; therefore, the candidate must conduct all work activities in compliance with AbbVie internal requirements and applicable regulatory requirements. 

Key responsibilities:  

  • Culture cells in a sterile environment, including the expansion, differentiation, and maturation of human iPSC-derived neurons 

  • Independently design and execute in vitro pharmacological studies; implement or innovate new experimental protocols as needed 

  • Perform in-depth data analysis, draw conclusions, and present findings to multidisciplinary teams 

  • Demonstrate critical thinking to troubleshoot and provide creative solutions to experimental challenges 

  • Collaborate with cross-functional team members to achieve organizational goals, ensuring excellence in execution and effective workload prioritization 


Qualifications

JOB QUALIFICATIONS (MINIMUM REQUIREMENTS): 

  • Highly motivated, hands-on experimentalist who thrives in a collaborative, multidisciplinary environment 

  • Demonstrates flexibility and a commitment to scientific excellence 

  • Possesses strong interpersonal and organizational skills, as well as creative thinking ability 

  • Able to perform experiments independently and work effectively in a team environment 

  • Interprets results and draws conclusions from multi-step experiments; notes significant deviations, uses scientific literature to suggest, design, and pursue relevant experiments 

  • Demonstrates meticulous attention to detail and diligence in record keeping 

Education and Experience 

  • Minimum of a bachelor’s degree in a biological science field with 5 years of experience in an academic or industry laboratory setting 

  • Expertise in aseptic techniques, including maintaining iPSC cell cultures is required 

  • Experience in cell transfection/transduction is preferred 

  • Expertise in executing enzyme-linked immunosorbent assays (ELISA), complex cell-based assays, and western blotting is required 

  • Experience with immunohistochemistry, microscopy techniques, and/or flow cytometry is preferred 

  • Computer skills: working knowledge of MS Office (Excel, Word, PowerPoint) is required 

  • Knowledge of graphing software (e.g., GraphPad Prism) and a basic understanding of statistical analyses are preferred 

  • Strong writing and communication skills 


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

  • This job is eligible to  participate in our short-term incentive programs. ​

Note: No amount of pay is  considered to be wages or compensation until such amount is earned,  vested,  and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a   particular employee  remains in the Company's sole and absolute discretion unless and until paid and may be  modified at the Company’s sole and absolute discretion,  consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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  • AbbVie will never request sensitive personal information (such as bank account details, social security numbers, or payment of any kind) during the recruitment process.
  • If you suspect you have received a fraudulent offer or communication claiming to be from AbbVie, please do not respond, open any attachments, or click on any hyperlinks.


If you have any questions or concerns regarding the authenticity of a communication alleged to have been made by or on behalf of AbbVie, please contact us immediately.


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Pay Range: $

75000 - 142500 USD