Scientist II, LNP Platform

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

We are currently hiring a highly motivated Scientist II to join our LNP Platform team. In this role, you will independently execute hands-on formulation and process development activities for emerging tLNP drug product programs, with a focus on high-quality execution, procedure adherence, risk identification, and practical problem solving.

This position will report to the Principal Scientist and based at our Worcester office. The role will involve hands-on laboratory work. All duties will be performed in compliance with AbbVie’s standard operating procedures (SOPs).

Experience in lipid nanoparticle formulation and purification processes, or experience with process development, engineering and manufacturing of biologics drug product processes, is highly desired.

Responsibilities & Duties:

• Execute defined technical projects and experimental plans focused on formulation, conjugation, purification, and process development for targeted lipid nanoparticle-based nucleic acid formulations.
• Prepare, formulate, purify, and characterize nucleic acid-based complex lipid nanoparticle formulations in accordance with established protocols, batch records, and SOPs.
• Execute, and analyze DOE-based and other structured experiments to develop and optimize LNP formulations, lyophilized drug products, and associated process parameters.
• Identify aberrant results, technical issues, process variability, or formulation performance concerns; support root-cause investigations; raise risks in a timely manner; and propose scientifically sound corrective actions.
• Maintain excellence in laboratory execution, including accurate preparation, timely completion of tasks, clear documentation of experimental procedures and results, and compliance with SOPs and other manufacturing-related documentation.
• Prepare high-quality technical reports and presentations that summarize procedures, study results, data interpretation, risks, and recommended next steps.
• Collaborate effectively within project and laboratory teams to deliver accurate, timely results and support short-term projects with defined technical problems.

• BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.
• Working knowledge of lipid-based delivery systems, formulation science principles, nanoparticle characterization, and/or drug product process development.
• Hands-on experience working with nucleic acid and/or lipid nanoparticle-based formulations, complex/nanoparticle formulations, and/or biological formulations development.
• Demonstrated ability to execute laboratory procedures with a high degree of accuracy, follow established protocols and SOPs, and maintain complete and compliant documentation.
• Ability to recognize technical risks, troubleshoot lab or process issues, conduct initial root-cause assessments, escalate concerns appropriately, and propose practical solutions.
• Ability to manage and complete multiple defined tasks or short-term projects under tight timelines while maintaining focus, quality, and attention to detail.
• Detail oriented with strong organizational skills and a commitment to excellence in execution of laboratory operations.
• Team player with excellent verbal and written communication skills, including the ability to clearly communicate progress, results, risks, and recommendations.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this roleat  the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on manyfactors  including  geographic location, and we may ultimately  pay more or less than the posted range. This range may be  modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to  participate in our short-term incentive programs.  ​

Note: No amount of pay is  considered to be wages or compensation until such amount isearned,  vested,  and determinable. The amount and availability of  any bonus, commission, incentive, benefits, or any other form of compensation and benefits that areallocable to a   particular employee  remains in the Company's sole and absolute discretion unless and until paid and may be  modified at the Company’s sole and absolutediscretion,  consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

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