Principal Research Scientist I, Depression Discovery

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

We are seeking an experienced and highly motivated scientist to join our Pharmacology and Cell Biology group within Discovery Psychiatry. The incumbent will be expected to oversee ongoing work in the group related to depression cell-based models, plan for future capabilities expansion, and may lead current or future drug discovery efforts. The ideal candidate will have experience with supervising scientific work, delivering high quality results and developing scientists. The position requires strong drug discovery experience and proven track record of leading multidisciplinary teams to progress projects through preclinical development. This is an excellent opportunity to work at the forefront of psychiatric research as part of a dynamic and growing team. 
Key Responsibilities: 

• Develop strategy and oversee implementation of internal models being used for depression drug development, especially in vitro iPSC-based models  

• Identify and solve technical problems independently, implement new assays and workflows, conceive and implement innovative research ideas 

• Supervise junior scientists, providing scientific and technical leadership in the design and execution of experiments, and be accountable for the effective development and performance of the team 

• Serve as biology lead for current or future drug discovery projects, responsible for coordinating cross-functional activities and representing team at governance forums from Hit Generation through Candidate Nomination 

• Provide input on the identification and selection of new targets, especially those related to depression 

• Collaborate with colleagues at various AbbVie and external sites 

• Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents  

• Ensure consistency and quality of technical reports 

Qualifications: 

• MS or PhD in Neuroscience, Biological Sciences, Pharmacology, or related discipline with typically 14+ (BS), 12+ (MS), or 6+ (PhD) years of experience in industry and/or academia 

• Strong background in psychiatry research and drug development, especially depression 

• Proven track record in progressing projects through preclinical discovery and into early development  

• Experience in working in multidisciplinary teams to accomplish strategic goals 

• Experience managing direct reports, including providing performance evaluations and development opportunities 

• Excellent organizational skills and the ability to manage multiple projects simultaneously 

• Demonstrated ability to collaborate effectively in a dynamic, cross-functional matrix environment 

• Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong “can-do” attitude 

Preferred Qualifications: 

• Experience in psychedelics research and drug discovery 

• Experience in overseeing and pioneering the use of novel in vitro iPSC-based models for psychiatry research 

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
• This job is eligible to participate in our long-term incentive programs. 

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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