Sr Scientist I, Biologics Purification and Characterization

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

The Biologics Discovery Sciences group at AbbVie is seeking a highly-motivated scientist to join a dynamic core team supporting biologics drug-discovery.  The role will be focused on purification of bispecifics candidates with suitable purity/characteristics to support advancement into in vitro studies (i.e. drug-like property assays, binding, cell-based assays, etc) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc).  The applicant must be proficient in all standard bioprocess and chromatography techniques at large scale (1g- 200g scale).  Responsibilities will include the design and execution of process development strategies necessary to address production liabilities and which factor in future process scalability.  The applicant will need to be an independent and creative problem solver who is proficient in overcoming issues (i.e. solubility, aggregation, recovery, purity) associated with purification of bispecifics candidates.  The role will also require intensive analytical characterization of molecules (end-products/process-intermediates) and extensive analytical methods development to characterize process and product related-impurities. The applicant should have a thorough understanding of how molecular- and post-translational attributes of bispecifics translate to their function.

The applicant should be able to work independently with chromatography software such as Unicorn, Chromeleon and Empower.  She/he needs to stay current with applicable internal/external scientific literature and apply new information in innovative ways to successfully complete work assignments.  The applicant should be able to analyze, document, and report data concisely and rigorously.  She/he should possess excellent communication skills and be proficient in presenting in front of groups.

Qualifications

• Bachelor’s Degree or equivalent education and typically, 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​​

• This job is eligible to participate in our short-term incentive programs. ​​

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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