Senior Scientist II, Antibody Engineering

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. 

• Lead from the lab and advance large molecule biologics projects from exploratory to optimization and drive Go / No Go decisions
• Effectively partner with functional and therapeutic areas to achieve project objectives
• Define scientific strategy within the biologics generation request team to discover and validate binders to a target of interest, including antibody and/or protein engineering, in vitro assays, in vivo proof of concept studies, and developability
• Multitask and work within timelines while maintaining a high level of productivity

• MS degree with 10 years of relevant experience or PhD with 4 years of relevant experience
• Demonstrated ability to use in vitro display technologies (phage, yeast, and/or mammalian) for discovery and/or engineering
• Knowledgeable in antibody sequence and structure to guide molecular evolution by experimental and/or AI/ML methods
• Proficient in sequence analysis from large datasets (Sanger, NGS) and DNA sequence analysis software (e.g. Geneious Prime)
• Proficient in screening molecular interactions, such as by ELISA, flow, and/or octet binding
• Excellent attention to detail, record keeping, and organization. Excellent communication, presentation, and collaboration skills.

Preferred Qualifications:

• Project leadership experience
• Structure-based molecular modeling and applications with AI/ML and integrating complex datasets to drive data-based decisions

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• ​This is an on-site role based out of AbbVie's South San Francisco offices. 
• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
• This job is eligible to participate in our short-term incentive programs. ​
• This job is eligible to participate in our long-term incentive programs​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html