Senior Scientist I - Drug Metabolite Identification

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. 

The Drug Metabolism and Disposition group in QTAS (DMPK) has an open position for a Scientist II/Senior Scientist I to perform drug metabolism studies supporting drug discovery and development. The selected candidate will be responsible for designing and conducting ADME investigations, interpret results, and apply knowledge to drive the pipeline and answer key scientific questions. The candidate will collaborate across various disciplines within AbbVie including DMPK, chemistry, biology, toxicology, pathology, clinical and regulatory to support biotransformation. It would be advantageous for the candidate to have practical experience performing all aspects of in vivo and in vitro biotransformation studies, mass spectrometry, structure identification, analytical method development, metabolite profiling, handling radioactive compounds, and possess strong written and oral communication skills. Duties will be focused on laboratory work and the applicant will collaborate across various disciplines within AbbVie.

Key Responsibilities Include:

• Design, perform, interpret, and report appropriate data of in vivo and in vitro studies for identifying metabolite structures and associated pathways
• Communicate data interpretation to DMPK colleagues, project teams and management
• Routinely operate LC-MS/MS instrumentation, including maintenance and troubleshooting.
• Potential to represent DMPK on cross functional project teams, drive compounds in development and responsible to answer key questions.
• Writing or contributing to study reports and regulatory submissions.
• Keeps well-informed of literature; Evaluate new methods, technologies, study designs and equipment.

• Motivated Ph.D. in life sciences, MS with 8+ years or BS 10+ years with relevant academic or industry research experience in small molecule development.
• Demonstrated expertise in mass spectrometry, liquid chromatography, and structure ID
• General understanding of DMPK processes, including method development, metabolite profiling, metabolic processes
• Strong interpersonal skills, the ability to work independently and work well within a team
• Strong presentation and written/verbal communication skills.
• Strong attention to detail
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation and manages innovation to reality

Key Leadership Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance 
• Learns fast, grasps the 'essence' and can change the course quickly where indicated
• Raises the bar and is never satisfied with the status quo
• Creates a learning environment, open to suggestions and experimentation for improvement
• Embraces the ideas of others, nurtures innovation and manages innovation to reality

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

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AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

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