Senior Scientist I – Cell & Molecular Biology (Dermatology)

At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit www.AllerganAesthetics.com.

Allergan Aesthetics R&D, Biological Research is seeking a highly motivated and innovative candidate for the role of Sr Scientist I – Cell and Molecular Biology.

The successful candidate will lead and contribute to the discovery and validation of targets in medical aesthetics, by developing and deploying cell and molecular biology techniques to evaluate therapeutic targets and testable hypotheses. He/she/they will participate in a team of scientists to lead and conduct various activities including target identification/validation and drug discovery using iPSC-derived cell systems, in vitro, ex vivo, -omics methodologies to evaluate pharmacology in collaboration with internal and external stake holders/experts. Prior experience in vitro models of the skin and/or hair are highly desired.

The candidate should be a highly motivated, hands-on experimentalist who is also capable to leading scientific projects and thriving in a multidisciplinary environment. Emphasis is on the ability to successfully perform hands-on work and lead discovery projects with minimal supervision, demonstrate scientific leadership skills and interact in a team environment. 

Key Responsibilities

• Lead and implement molecular and cell biology models to support target validation and progression of early-stage targets in medical aesthetics.
• iPSC culture and differentiation strategy and execution for hair follicle biology projects
• Research and understand relevant target/disease biology; design and implement experimentation to validate hypotheses.
• Prepare presentations and represent the group to cross-functional teams.
• Train and mentor research associates when appropriate
• Maintain awareness of current developments in the field through comprehensive reading and analysis of the literature and attendance at appropriate scientific meetings.
• Understand the competitive landscape and participate in the review and analysis of outside opportunities.

Minimum Qualifications:

• Ph.D. or Masters in cell and molecular biology or equivalent subject
• 0+ years of experience with PhD OR 8+ with Masters (academic/postdoc or industry)
• Experience in dermatology or developmental biology or pharmacological evaluation of drugs
• Extensive experience in mammalian tissue culture with a focus on iPSC culture and differentiation as well as complex cell models to evaluate function.
• Experience in analysis of big data sets (NGS, -omics, etc.) 
• Translational in vitro functional assays with primary cells and the application of these techniques to pharmacological studies is required.
• Experience with qPCR, western blot, ELISA, Luminex and immunofluorescence techniques

Preferred Skills:

• Experience with siRNA design/ CRISPR assays and implementation in target validation and functional studies.
• Experience in drug development setting

Other Required Skills:

• Strong scientific skills with the ability to collaborate with project team members.
• Must be able to multitask effectively and be adaptable and flexible to meet changing priorities.
• Motivated team player with a can-do attitude.
• Must have excellent written and oral communication skills.
• Committed to the values of integrity, accountability, transparency, scientific rigor and drive. 

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

• This job is eligible to participate in our long-term incentive programs​

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

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