Scientist II (all genders) Process Engineering Sciences in Biologics Product Development Science & Technology (permanent / full-time)

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. 

The job that makes possibilities real in patients' lives. And yours.

The job that helps you get ahead in life. Moving mountains together.

Welcome to AbbVie! As part of an international company with 48,000 employees worldwide and around 3,000 employees in Germany, you will have the opportunity of addressing some of tomorrows unmet medical needs in close collaboration with your colleagues. Are you passionate about improving global health care? Do you want to contribute to improving patients' quality of life through your expertise? In a challenging work environment that offers opportunities of developing and increasing your own skills? You’ve come to the right place!

Moving mountains together – as Scientist II (all genders) Process Engineering Sciences in Biologics Product Development Science & Technology (permanent / full-time)

We are looking for a Process Engineer who is focusing on process development to support the project needs in fill-finish-manufacturing of biologics, applying theoretical and scale-down-models as appropriate. 

AbbVie has a strong, established expertise in the development of injectable drug products in syringes, cartridges, or vials. Over the past three decades, AbbVie and its legacy entities made significant progress to advance its formulation and process development from empirical approaches to increasingly incorporate more in-silico and model-based techniques. Being a highly agile and efficient development organization, AbbVie Biologics Drug Product Development continuously seeks opportunities to implement in-silico research tools, develop deep process understanding to speed up and de-risk development of drug products in all project phases.  

The Process Engineering (PE) Group was established to form an alliance of an engineering perspective with biopharmaceutical development. Depending on the background, the scientist gets the opportunity to introduce new methods regarding small-scale models as well as computational modeling (e.g., digital twins) into process development. The main area will be the support of the biologics drug product development for injectable drugs with a focus on heat transfer, thermo- and fluid dynamics being applied to freezing and thawing, mixing, sterile filtration, pumping, filling and lyophilization. The position will incorporate process simulation and hands-on bench experiments. Experimental and manufacturing data will be translated into the development of digital twins to result in optimized computational models to advance processes. 

As Scientist, you passionately drive projects in an integrated environment among distinct subject matter experts in fields such as CFD modeling, material science and physical pharmacy, as well as experts in various analytical techniques. 

Responsibilities

• Support projects with focus on machine-oriented process engineering topics from troubleshooting to application of small-scale models and computational models 

• Serve as fill-finish expert within Product Development, Science and Technology and contact person to early-stage R&D as well as Drug Substance Manufacturing 

• Global and cross functional support of other development groups in model application, tech transfer to production, up-/downscaling, troubleshooting, generation of regulatory filing documents 

• Propose, engineer, build, test prototype machines, combine with existing equipment, integrate them in overall modular workflows, combine with e.g. 2D visual camera systems, assure automatic data generation, storage and evaluation 

• Help the organization to understand and implement simulations (from Excel sheets to CFD, DEM, FEM, …) into a routine development philosophy 

• Generate data from bench experiments and/or gather data from machines in pilot plant, internal or external runs on commercial equipment 

• Use of Quality by Design (QbD) approach, strive for simplicity and efficiency, apply Lean and/or scrum principles 

• Independently work on scientific topics, screen, assess and implement novel technologies, drive global initiatives and present results convincingly to diverse audience 

• Propose, develop and implement strategies for process optimization (machine / fill finish oriented processes as well as work processes like generation, processing, data extraction and storage of reports); explore options of AI / deep learning integration 

• Active participation in all development phases with focus on late stage projects and technical transfer to commercial production  

• Supervision of interns and bachelor/master students 

• BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience
• Degree in engineering, or equivalent with experience in industry (pharma or biopharma)
• Track record of significant process improvements (from concept through implementation)
• Experience in process engineering and/ or combination product development
• Experienced in DoE, QbD, Statistics,
• Skilled in Lean / Scrum principles
• Knowledgeable in AI / deep learning
• Sound understanding of individual fill-finish related unit operations and their practical implementation, to ensure the design and procurement of the equipment to the determination of product- and scaleup-specific process parameters. 
• Structured thinking driven by first principles (physics, physico-chemical, thermodynamic…)
• Independent way of working with strong decision skills while being efficient team leader as well as team member
• Present results to a broad audience from different areas via presentations, posters and/or reports 
• Able to develop quick, minimally viable packages to convince organization of working concepts, while still driving project towards the long-term goal
• Willing to integrate in a team with a strong will to improve processes and efficiency
• Experience with biotechnological manufacturing processes (from lab via pilot up to commercial scale) and associated analytics
• Pragmatic, smart decision making in relation to "good enough for this purpose"
• Proficient spoken and written English skills
• Excellent German language skills

Here's how we can move mountains together

• with a diverse work environment where you can have a real impact
• with an open corporate culture
• with an attractive salary
• with an intensive onboarding process with a mentor at your side
• with flexible work models for a healthy work-life balance
• with a corporate health management that offers comprehensive health and exercise programs
• with company social benefits
• with a wide range of career opportunities in an international organization
• with top-tier, attractive development opportunities
• with a strong international network

Multiple times, we have been globally recognized as a "Great Place to Work" and we are proud to provide our employees with the flexibility to maintain a healthy work-life balance. We take our impact on the environment and our communities seriously and therefore focus on giving something back on a regular basis. We are committed to equality, equity, diversity and inclusion (EED&I) – a commitment that is fundamental to us. This includes appreciating different perspectives, creating an inclusive culture and treating all employees with dignity and respect.

At AbbVie, your individual contributions count – help us move mountains together. Be a part of our success, grow with us and accomplish more than you could have imagined. Sounds like the perfect career opportunity for you? We look forward to receiving your application! All you need is a complete CV – we will discuss everything else with you in person.

Any questions? Feel free to email as at TalentAcquisition.de@abbvie.com – we look forward to hearing from you!

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html