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Scientist, Cell/Molecular Biology

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South San Francisco, CA

  1. Research & Development
  1. Full-time
REF49651Z

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on XFacebookInstagramYouTubeLinkedIn and Tik Tok.


Job Description

Key Responsibilities

  • Execute in vitro or ex vivo experiments to validate novel targets using cell lines & primary human cell sources.
  • Perform cell culture (suspension & adherent) & assays including but not limited to: DNA/RNA/protein purification, siRNA/CRISPR knockdowns, Lentiviral transfections, immunoprecipitation, WES, western blot, ELISA, MSD, HTRF, quantitative PCR, protein degradation & colorimetric assays.
  • Collect, analyze, & summarize data for presentations, & reports.
  • Maintain an up-to-date understanding of new technologies & relevant scientific advances in tumor dependencies & its roles in cancer from literature & scientific meetings.

Qualifications

Education & Experience

Must have a Master's degree in Cellular & Molecular Biology, Cancer Biology, Pharmaceutical Sciences, Pharmacology, or related field & 2 years of experience as a Scientist. Of experience required, must have 2 years: (i) performing mammalian cell culture in a biosafety level 2 environment; (ii) performing (a) western blotting, immunoprecipitation, WES, or ELISA, (b) DNA/RNA isolation, RT-PCR, separation techniques for primary cells, & (c) gene expression analysis; (iii) handling & processing human tissue samples for biological assays; & (iv) developing, optimizing, & troubleshooting cell-based assays. Of experience required, must also have 1 year: (i) manipulating gene expression by CRISPR methods in cancer cell types; (ii) utilizing the biological data analysis software tool: GraphPad Prism & at least one of the software tools: Excel, Image Studio, Spotfire, or Compass; & (iii) documenting experimental procedures & methodologies for regulatory filings. Work experience may be gained concurrently.


Additional Information

Salary: $125,508.24 - $138,500.00 per year

Apply online at https://careers.abbvie.com/en or send resume to Job.opportunity.abbvie@abbvie.com. Refer to Req ID: REF49651Z

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We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.  This job is eligible to participate in our short-term and long-term incentive programs.

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

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