Scientist (Biochemistry – High Throughput Antibody Production)
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Worcester, MA
- Operations
- Full-time
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Key Responsibilities
- Manage antibody production campaigns in collaboration w/therapeutic areas, incl. data mgmt, presentation & coordination of assays to be run.
- Execute high throughput molecular cloning & antibody production workflows using automation technologies.
- Lead dvlpmt of new automated liquid handling or analytical workflows.
- Characterize therapeutic proteins using MS, SEC, DSF, ELISA, SDS-PAGE, FACS.
Education & Experience
Must have a Master's in biology, biochemistry or related field & 2 yr research or industry exp in:
(i) Applying molecular biology techniques (PCR, molecular cloning);
(ii) Utilizing sequence analysis tools (Vector NTI, Geneious, Sequencher), graphing software (GraphPad Prism) &statistical analysis (Python);
(iii) Applying cell culture (bacteria, mammalian) & protein purification techniques (AKTA, Protein Maker, Assay MAP);
(iv) Conducting analytical characterization of therapeutic proteins (MS, SEC, DSF, ELISA, SDS-PAGE); and
(v) Conducting statistical (Python) and structure-based (PyMol, Schrodinger Bioluminate) analysis of protein structure and function to predict liabilities and features of interest in antibodies.
Of experience required, must also have 1 yr research or industry exp utilizing and developing methods on liquid handling platforms (Hamilton, Tecan, Dynamic Devices).
Experience may be gained concurrently.
Salary Range: $104,200 - $138,500 per year.
Apply online at https://careers.abbvie.com/en. Refer to Req ID: REF39458D.
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We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term and long-term incentive programs.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html