Principal Research Scientist I, Chemistry

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn. 

AbbVie Product Development Science & Technology (PDS&T) conducts late-stage process development, supporting projects from registration through commercialization and throughout the product lifecycle. PDS&T is seeking a Principal Research Scientist (Chemistry) who is highly motivated, with a proven track record of accomplishment in the field of chemical manufacturing development, to work in a multi-functional team environment at our North Chicago, IL location.

• The candidate will be responsible for developing organic chemistry processes for the manufacture of small molecule drug substances (Active Pharmaceutical Ingredients), as well as developing appropriate control strategies and supporting manufacturing on pilot to commercial scale to provide practical access to potential therapies.
• The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, and solid-state scientists.
• The position also entails interfacing with many groups external to PDS&T, for example: Manufacturing Operations, Regulatory Affairs, Quality Assurance, etc.

Responsibilities:

• The candidate will work within and/or lead cross-functional project teams associated with manufacturing process development, process characterization/justification, transfer of technology to manufacturing sites, and support manufacturing activities of API for commercial products.
• Effectively functions as a principal investigator, generating original technical ideas and demonstrating creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. Make significant contributions to project team through lab-based activities. Independently responsible for project science within his/her area of expertise on one or more project teams.
• Authors and/or reviews technical reports, manufacturing batch records and regulatory documents concerning Chemistry, Manufacturing and Control (CMC) subjects. Primary author of publications, presentations, and/or primary inventor of patents.
• Mentor/supervise a team of one or more individuals, evaluate the performance of those individuals and be accountable for the effective performance of those individuals.
• Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.

• Bachelor’s Degree or equivalent education and typically 14+ years of experience; master’s degree or equivalent education and typically 12+ years of experience; PhD and typically 6+ years of experience in organic chemistry. Candidates with less experience may be considered for other opportunities.
• The successful candidate will have a strong understanding of chemical manufacturing process development, specification setting, starting material justification, and control strategy development consistent with modern expectations for pharmaceutical development.
• A broad range of functional expertise in modern synthetic organic chemistry, mechanistic understanding, compound purification, and standard analytical methodology (HPLC, UPLC, LC-MS, NMR).
• Demonstrated scientific communication and presentation skills by presenting at leading scientific conferences. Experienced and demonstrated success as author of publications, presentations, and/or primary inventor of patents. Recognized and sought out as an expert in his/her discipline.
• Strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams.

Key Leadership Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, understands key objectives, and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation, and manages the transition from innovation to implementation.
• Understands, adheres to and models corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug compounds, and GxP compliance.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

• This job is eligible to participate in our long-term incentive programs​

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion.  It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html 

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