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La missione di AbbVie intende scoprire e fornire medicine innovative per risolvere gravi problemi di salute attuali e gestire le sfide sanitarie di domani. Puntiamo ad avere un rilevante impatto sulla vita delle persone in diverse aree terapeutiche fondamentali: immunologia, oncologia, neuroscienze, oculistica, virologia, salute della donna e gastroenterologia, oltre a fornire prodotti e servizi al portafoglio Allergan Aesthetics. Per maggiori informazioni su AbbVie, visita l’indirizzo Seguici @abbvie su Twitter, Facebook, Instagram, YouTube e LinkedIn.

Principal Scientist I, Precision Medicine

South San Francisco, California ID dell'offerta 2115255 Categoria Research and Development Divisione AbbVie

Position Description

We are seeking a highly motivated scientist with expertise in Oncology, Immuno-Oncology, Hematology-Oncology or related field. In this role, you will join an experienced team and will work closely with the Precision Medicine Lead to implement biomarker efforts in support of Abbvie sponsored clinical trials. The ideal candidate will have experience in the development and execution of successful biomarker strategies in oncology trials. 


  • Lead implementation of biomarker strategies for one or more clinical trials and serve as point of contact for all aspects of clinical biomarker strategy providing scientific expertise and leadership to programs
  • Work in cross-functional teams with clinical, translational and discovery groups to design high quality clinical biomarker strategies to deliver on project needs
  • Implement standard and innovative tools to identify biomarkers to characterize drug mechanisms, define patient selection strategies, and support back translational research
  • Author biomarker sections of protocols, ICFs, IRB responses, regulatory documents, and scientific publications
  • Present biomarker proposals and analyses to cross-functional teams; present at scientific conferences 
  • Pro-actively consult primary scientific literature, keeping current on state of art technologies and emerging concepts in oncology


  • PhD, MD or PhD/MD degree in life sciences (oncology, immunology, pathology, molecular biology, cell biology) and 6+ years industry experience of biomarker research in a clinical setting, preferably related to immunology or cancer biology
  • Broad scientific and technical expertise in tumor cell biology, immune cell biology, and clinical trial design or execution


  • Strong scientific background in tumor biology and immuno-oncology supported by publication record in these areas
  • Clinical development experience interacting with teams conducting clinical trials
  • Demonstrated leadership in translational sciences, employing pharmacodynamic, predictive and exploratory biomarkers
  • Experience in assay development, qualification and implementation of biomarker assays on diverse platforms including IHC/IF, gene expression profiling, flow cytometry
  • Effectively work in a cross-functional team environment, interacting with various levels within the organization as well as vendors/academic sites/KOLs
  • Organization, orientation to details, and effective time management with an ability to adapt to changing priorities
  • Excellent written and oral presentation skills in the English language
Significant Work Activities: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel: No
Job Type: Experienced
Schedule: Full-time

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