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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Sr. Scientist I - Cell Line Development

Worcester, Massachusetts Req ID 2206220 Category Research and Development Division AbbVie

The CHO Cell Line Development group at the AbbVie Bioresearch Center in Worcester, MA is seeking a highly motivated and experienced Senior Scientist to join our team. The Senior scientist will advance AbbVie’s biotherapeutics pipeline through the development and characterization of highly-productive recombinant CHO cell lines suitable for cGMP protein manufacturing. The selected candidate will have a major role in cell and process optimization, focused on new methods and technologies (e.g., targeted integration, host cell engineering) to significantly enhance productivity, efficiency, quality, and timelines.  A strong candidate will have in-depth experience in mammalian cell genetic engineering, genetic characterization and/or bioinformatics. 

Responsibilities:

  • Develop and characterize highly-productive stable CHO cell lines suitable for cGMP biotherapeutic manufacturing within project timelines. 
  • Conceive, investigate and execute scientific research and development to improve cell and process productivity, efficiency, robustness and product quality; develop new methods, build technical expertise and intellectual property, and deepen scientific understanding.
  • Effectively collaborate and communicate with colleagues within and across functions.
  • Routinely demonstrate scientific initiative and creativity in research or development activities.
  • Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
  • Formulate conclusions and design follow-on experiments based on multidisciplinary data.
  • Initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program.
  • Demonstrate high proficiency across a wide range of relevant technologies.
  • Maintain a high level of productivity in the lab.
  • Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.
Qualifications:
  • Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
  • Possess thorough theoretical and practical understanding of own scientific discipline.
Significant Work Activities: N/A
Travel: No
Job Type: Experienced
Schedule: Full-time
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