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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Senior Scientist, in vitro

Primary Worcester, Massachusetts Req ID 2212019 Category Research and Development Division AbbVie

AbbVie Immunology has discovery efforts focused on antibody-drug-conjugates (ADC) for the treatment of fibrosis, with a focus on systemic sclerosis/scleroderma and idiopathic pulmonary fibrosis. The ADC research group will focus on developing in vitro models of fibrotic disease as well as screening assays to validate ADCs. We are seeking a bench scientist with extensive in vitro skills who can develop and execute on a variety of different assays to support this area of research.  The ideal candidate will thrive in a highly collaborative environment that includes biologics, chemistry and bioinformatics.

Key Responsibilities Include:

  • Independently develop, optimize and implement in vitro approaches to study human fibrotic disease to demonstrate therapeutic efficacy
  • Expertise with cell culture, particularly with primary human cells
  • Develop and execute screening assays to validate ADCs


  • Bachelor’s Degree or equivalent education and typically 10-12 years of experience, Master’s Degree or equivalent education and typically 8-10 years of experience, PhD and typically 0-4 years of experience.
  • Understanding of biologics/large molecule approaches for therapeutic interventions
  • Experience developing/executing in vitro assays for screening as well as demonstrating therapeutic effects in cell-based systems
  • Prior experience with biologics or fibrosis is a plus
  • Prior drug discovery/industry experience is a plus
  • Excellent written and oral communication skills, including data analysis, record keeping in an electronic notebook and presentation of work at project team meetings
  • Collaboration skills

Key AbbVie Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance
  • Learns fast, grasps the “essence” and can change the course quickly where indicated
  • Raises the bar and is never satisfied with the status quo
  • Creates a learning environment, open to suggestions and experimentation for improvement
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality

Position will be hired based on level of experience. 

Significant Work Activities: N/A
Travel: No
Job Type: Experienced
Schedule: Full-time

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