Skip to main content

Search jobs

Search jobs

About AbbVie

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Senior Scientist I/II

Worcester, Massachusetts Req ID 2207414 Category Research and Development Division AbbVie

The Biologics Drug Biology Group at AbbVie is seeking a highly motivated research scientist to join the Multi-specific Biologics Platform team. This position is located at AbbVie Bioresearch Center in Worcester, MA. The desired candidate will play an important role in supporting the multidisciplinary groups across AbbVie focused on developing therapies for Immunology, Virology, Neurology and Oncology diseases. The Multi-specific Biologics Platform team is a multi-functional group across sites that utilize innovative protein engineering tools to produce next generation bispecific molecules for therapeutic indications. The scientist will be responsible to design and optimize multi-specific drug candidates supported by structural modeling of protein-protein interactions.

Responsibilities

  • Engineering of multi-specific biologics utilizing IgG scaffolds, through knowledge of protein biochemistry/biophysics and in silico structural modeling
  • Perform protein production and multi-step purification to produce high quality materials
  • Characterize proteins using SE-HPLC, SDS-PAGE and endotoxin assays
  • Demonstrate skills in analyzing, interpreting, and communicating experimental data and effectively presents scientific concepts and results.
  • Record and document accurate experiment results in a timely manner

Position will be hired based on level of experience.

  • BS, MS or PhD in Biochemistry/Biophysics or other related field with typically 10-12 (BS), 8-10+ (MS), or 0-4+ (PhD) years of experience
  • Expertise in protein engineering with experience in structural biology and computational modeling of protein-protein interactions
  • Experience with protein analysis techniques such as SE-HPLC, mass spec and SDS-PAGE
  • Ability to operate AKTA purification systems for protein purification
  • Experience in X-ray crystal analysis, NMR or Cryo-EM is a plus
  • Excellent communication, interpersonal and organizational skills
  • Hands on experience with liquid handling robots is a plus
  • Experience in molecular biology and plasmid construction a plus
  • Experience in non-antibody scaffold proteins is a plus
  • Excellent attention to details and the ability to communicate effectively
Significant Work Activities: N/A
Travel: No
Job Type: Experienced
Schedule: Full-time
ABBVIE

Most recent jobs

Sign up for job alerts

Join our talent network and receive AbbVie news and job alerts to your inbox.

Interested InPlease select a category or location option. Click “Add” to create your job alert.

  • Research and Development, Worcester, Massachusetts, United StatesRemove

Our Terms of Use, Cookie Policy and Privacy Policy explain how we collect and use information about you and the rights you have. By submitting your information, you acknowledge you have read those documents and consent to receive SMS communications and email jobs alerts from AbbVie.

Recently viewed jobs

You have not viewed any jobs recently.

Phishing scam alert

As an online job seeker, you could be a target of cyber (online) thieves seeking to secure personal information from you by sending you “phishing” messages.

Please be alert to and protect yourself from phishing scams. Find out how you can avoid being a victim of job phishing scams.

For Internal Candidates only - Notice of Filing of Labor Condition Application

Equal Employment Opportunity | Reasonable Accommodation