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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Scientist I Precision Medicine Translational Research Molecular Biology

Worcester, Massachusetts Req ID 2115297 Category Research and Development Division AbbVie

The Precision Medicine Department is committed to advancing drug development and patient care through building a deeper understanding of disease biology and developing tools to optimize clinical decision making and customize treatment for patients. The Scientist will be part of a fast paced and multi-disciplinary team responsible for developing and implementing new technologies to enable decision making in clinical trials, and evaluate disease and drug biology. The successful candidate will have a demonstrated ability to design, execute, troubleshoot, and interpret experiments independently. The successful candidate will have expertise in advanced molecular techniques such as next generation sequencing and instrument automation. The successful candidate will also have experience with handling human tissues and samples, and developing assays to evaluate drug target engagement, receptor occupancy and pharmacodynamics, and interrogate disease and drug biology. 

Key Responsibilities:

  • Maintain a high level of productivity in the laboratory
  • Independently design, execute, and interpret critical experiments to answer scientific questions
  • Demonstrate the ability to resolve project hurdles by utilizing available information and technical expertise in molecular biology
  • Analyze and document results, placing data in proper scientific context through review of relevant literature and report findings at team meetings
  • Understand and adhere to corporate standards regarding code of conduct, safety, controlled drugs and radioactive compounds
Qualifications:

Qualifications:

  • Bachelor’s Degree or equivalent education and typically 2+ years of experience, Master’s Degree or equivalent education and typically 0 years of experience
  • Experienced in RNA isolation, qPCR, and RNAseq
  • Experience working with human tissues
  • Experience with scRNA-seq or CITE-seq, or instrument automation for library preparation (Beckman Biomek i7) is a plus
  • Knowledge of target engagement, receptor occupancy and pharmacodynamic assay development is a plus
  • Knowledge of basic immunology concepts
  • Ability to work with multidisciplinary groups in a fast-paced discovery team setting
  • Effectively communicate cross-functionally with team members throughout the organization
  • Demonstrated ability to communicate effectively (both written and oral)

Equal Opportunity Employer Minorities/Women/Veterans/Disabled
 

Additional Information:

  • Travel: No
  • Job Type: Experienced
  • Schedule: Full-time

 

 

Significant Work Activities: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel: No
Job Type: Experienced
Schedule: Full-time
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