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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Associate Scientist II/Scientist I, Cellular/Molecular Biology

Worcester, Massachusetts Req ID 2211415 Category Research and Development Division AbbVie

We are seeking a highly motivated Associate Scientist/ Scientist to join the AbbVie Drug Discovery Science & Technology organization. The successful candidate will be part of an exciting and fast-paced team working with cross-disciplinary groups both internally and externally with a primary focus on biology of aging. This individual will provide dedicated support to the Biologics Drug Biology group through protein production and analysis to explore novel therapeutic approaches to age-related diseases. Experience in protein purification and characterization is required.

Responsibilities:

  • Perform purification on AKTA FPLC systems using Unicorn software, design and modify protocols as needed
  • Characterize purified material using techniques such as SE-HPLC, SDS-PAGE and MS
  • Perform biochemical binding assays (such as ELISA, MSD, Western-blots or WES) to characterize biologics molecules.
  • Maintain, propagate and bank mammalian expression cell lines
  • Order expression constructs or perform molecular cloning as needed
  • Collaborate with colleagues and outside vendors in the set-up and maintenance of relevant laboratory instruments
  • Engage colleagues in cross-disciplinary scientific discussion, present scientific data to internal and external audiences.
  • Keep accurate electronic records of experiments and activities, timely report experimental results.
  • Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug and radioactive compounds, GxP compliance, and animal care where applicable.

Qualifications:

  • B.S. in Biochemistry, Molecular Biology, or equivalent discipline with 3-5+ years of experience; MS in equivalent field with 0-2+ years of experience
  • Proficiency in protein purification on AKTA FPLC machines and Unicorn software as well as analytical techniques such as SE-HPLC and MS is required
  • Experience with mammalian or bacteria cell culture is required
  • Hands on experience with plate-based assays such as ELISA, MSD is desired.
  • Ability to work both independently and as a member of a multidisciplinary matrix team in a dynamic and fast-paced environment, desire to take on increasing responsibility over time.
  • Excellent collaboration and organizational skills are required.
  • Competency with sequence analysis software programs including Geneious is a plus.

Position will be hired based on level of experience.

Significant Work Activities: N/A
Travel: Yes, 5 % of the Time
Job Type: Experienced
Schedule: Full-time
ABBVIE

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