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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Senior Scientist II/Principal Research Engineer I, Process Engineering Sciences

North Chicago, Illinois Req ID 2210312 Category Research and Development Division AbbVie

Drug Product Development is responsible for developing manufacturing processes that enable delivery of AbbVie’s candidate molecules in a dosage form which is intended for product commercialization. We have an exciting opportunity for a Senior Scientist II/Principal Research Engineer in the Process Engineering Sciences group based in North Chicago, IL. AbbVie is seeking a highly motivated, collaborative scientist with a proven track record that can optimize manufacturing processes and lead projects for small molecules.

Key responsibilities include: 

  • Lead the drug product manufacturing process optimization for small molecule development candidates within the AbbVie pipeline.
  • Collaborate with drug product development CMC teams to ensure formulation and manufacturing process are amenable with the intended commercial manufacturing sites.
  • Advance scientific expertise within function. Proactively demonstrate leadership by advising and sharing knowledge and expert opinions with subordinates, peers, and senior management.
  • Ensure development of technologies and scientific innovation that improve the capability to formulation small molecules within the AbbVie pipeline
  • Collaborate with other functions within AbbVie to align a broad range of strategies that directly support drug discovery and development programs
  • Ensure compliance with AbbVie safety, quality and regulatory policies and government regulations.

Position can be hired as a Senior Scientist II or Principal Research Engineer I based on the candidate's level of education and years of experience. 


  • BS or equivalent education and extensive, typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; PhD with typically 6+ years of experience in area or scientific area of discipline.
  • Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies.
  • Demonstrate creative 'out of the box' thinking to solve difficult technical problems and champion new technologies to achieve project goals.
  • Recognized and sought out as an expert in his/her discipline within the company and possibly externally.
  • Experienced and demonstrated success as primary author of publications, presentations, regulatory documents and/or primary inventor of patents.
  • Demonstrated scientific communication and presentation skills by presenting at leading scientific conferences.


  • Strong project leadership experience for dry solid oral drug product development.
  • Advanced understanding drug product manufacturing platforms including direct compression, wet & dry granulation, and hot melt extrusion.
  • Advanced understanding of powder material properties and their impact on drug product manufacturability and final product performance.
  • Ability to apply/interpret models during drug product development to optimize development.
  • Demonstrated ability to troubleshoot process/material issues.
  • Apply techniques to scale-up the development process to commercial equipment.
  • Displays technical awareness in various aspects of drug development, adherence to rigorous scientific method, and commitment to the scientific process.
  • Strong drive for learning new techniques and technologies.
  • Excellent oral and written communication skills.
  • Demonstrated ability to work collaboratively in a cross-functional team setting.

Significant Work Activities: Keyboard use (greater or equal to 50% of the workday)Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel: Yes, 10 % of the Time
Job Type: Experienced
Schedule: Full-time

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