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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Pharmacokinetic Analyst - Scientist I (DMPK-BA)

North Chicago, Illinois Req ID 2207310 Category Research and Development Division AbbVie

The Drug Metabolism, Pharmacokinetics & Bioanalysis (DMPK-BA) team at AbbVie, Inc. is seeking a Pharmacokinetic (PK) analyst to join the Early PK and PK Logistics group at our corporate headquarters in the Chicago area.  The successful candidate will be responsible for designing pre-clinical animal PK studies and processing the data into viable report packages for project teams.  You will be expected to work closely with multiple key partners (i.e. DMPK project representatives, formulation scientists, pre-clinical safety, comparative medicine, etc.) to effectively and efficiently execute these pre-clinical studies. Applicants should have a strong foundational knowledge of pharmacokinetic principles and study design. The ideal candidate will preferably have some background in animal welfare and pre-clinical drug development.

Key Responsibilities:

  • Provide logistics and support to design, schedule, and execute pre-clinical animal studies across US-based research sites including PK, Pharmacodynamic (PD), efficacy, and Toxicokinetic (TK) studies.
  • Process, analyze, and report pre-clinical animal PK data
  • Interpret results through close partnership with DMPK-BA project representatives and support project teams across multiple therapeutic areas.
  • Collaborate with AbbVie’s Institutional Animal Care and Use Committee (IACUC) to align and implement industry leading standards for all pre-clinical animal studies
  • Communicate effectively and clearly both internally and externally PK study designs and PK data analysis.
  • Maintain excellent practices across all documentation platforms including electronic lab notebooks and analysis software.
  • Write, review, and contribute to pre-clinical study protocols and regulatory filing documents.
  • Stay current with latest developments in the field of DMPK and pre-clinical animal studies. 

Qualifications:

Basic:

  • Bachelor’s Degree in a relevant field (e.g. biological or pharmaceutical sciences) or equivalent education with typically five (5) years of experience, or Master’s Degree or equivalent education with typically two (2) years of experience

Preferred:

  • Background in pharmacokinetics and pharmaceutical sciences
  • Hands-on experience with pre-clinical animal study design and PK data analysis is preferred
  • Experience with relevant analysis software, including PK Plus, Winward, and Phoenix WinNonlin is a plus
  • General understanding of in vitro and pre-clinical in vivo ADME/PK
  • Passion for data analysis, solving problems and applying new technologies to further scientific goals
  • Proven ability to work in a team environment; ability to work well in a collaborative fast-paced team environment
  • Demonstrated scientific writing skills and strong verbal communication skills
  • Highly motivated, result-oriented person and independent thinker with proven ability to work cross-functionally and with other stakeholders
  • Thorough theoretical and practical understanding of own scientific discipline

Key Leadership Competencies:

  • Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Significant Work Activities: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel: No
Job Type: Experienced
Schedule: Full-time
ABBVIE

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