Investigative Pathologist

AbbVie's Investigative Toxicology group is an innovative, functional, and integrated scientific team contributing to the advancement of the overall portfolio. The Investigative Pathologist will focus on providing Discovery teams with integrated strategic preclinical safety plans, conduct studies to characterize toxicity, and assessing anatomical histopathology for potential drug effects.  Key responsibilities include early screening of experimental molecules to understand potential toxicities impacting preclinical safety and the ability to integrate in vitro and in vivo toxicity data.  The ability to collaborate across teams in a matrix environment is essential.

Essential Job Function/Description:

• Evaluate microscopic slides and clinical pathology data and communicate pathology findings to project teams
• Provide leadership for early target and compound toxicologic characterization by functioning as the nonclinical safety point-of-contact for Discovery projects, responsible for the design and communication of project strategies and testing plans
• Conduct hypothesis-driven preclinical safety characterization to enable accelerated decisions regarding target viability and internal prioritization of early lead molecules
• Partner with key allied functions (e.g., DMPK, formulation scientists) for strategic design and implementation of experimental plans and protocols
• Ensure alignment between preclinical safety and Discovery colleagues ensuring smooth and efficient advancement of projects to Early and Mid-Development stages
• Lead cross-functional efforts to investigate the underlying mechanism and relevance of in vitro and in vivo toxicology data generated in state-of-the-art laboratories
• Partner with regulatory toxicologists, molecular toxicologists, safety pharmacologists and other functions to develop optimal strategies to address specific issues as well as select and advance Development compounds
• Maintain a strong, externally recognized reputation in the field of investigative pathology and toxicology
• Represent AbbVie in industrial consortia and professional organizations focused on improving nonclinical safety assessment

Qualifications

Basic

• DVM and ACVP certification.
• Excellent oral and written communication skills
• Proven record of scientific contributions to the biomedical research community
• Ability to bridge between the Discovery and Development environment
• Ability to lead multidisciplinary scientific teams and operate independently in a matrixed environment

Preferred

• PhD in Toxicology, Pharmacology, or related field
• DABT certification
• Experience in Drug Discovery/Development