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AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Senior Scientist II, Ophthalmology Multi-omics Data Application

Primary Irvine, California Req ID R00092552 Category Research and Development Division AbbVie

AbbVie’s Ophthalmology Discovery Research group is looking for a highly motivated and experienced ocular scientist with a multidisciplinary background in bioinformatics to play an integral role in target identification and early drug development of therapies for ophthalmic diseases. This position offers an exciting opportunity to contribute to the growth of Ophthalmology Discovery Research in multi-omics data generation and integration to advance the understanding of disease pathology.  The successful candidate will enable synergies between drug discovery and bioinformatics and support our research group as a liaison with bioinformatic partners at different AbbVie locations.

This position will be based in Irvine, California, and the candidate will have the opportunity to work in a fast-paced, highly collaborative environment to leverage cutting-edge multi-omics technology. The successful candidate will support research activities, applying cellular or molecular biology techniques, and lead projects in collaboration with internal and external stakeholders/expertsThe candidate will be responsible for working with cross-functional teams to help integrate biological and computational approaches to facilitate preclinical experimental design in models and human donor samples, interrogate omics-datasets in coordination with bioinformaticians, coordinate research activities across multiple ocular indications, and formulate workflows for data integration into the AbbVie networks. The successful candidate will preferably have proficiency with multiple omics data types. 


Duties and Responsibilities: 

1.       Conduct research on ocular diseases using both cellular/molecular biology and bioinformatics tools and techniques. 

2.       Act as a liaison with cross-functional teams, including biologists, geneticists, and bioinformaticians, to design experiments and perform data analysis. 

3.       Perform data mining, integration, and visualization to identify patterns and extract meaningful insights from ocular datasets. 

4.       Contribute to the development of innovative approaches and the latest advancement in ocular research. 

5.       Prepare scientific reports, manuscripts, and presentations. 

6.       Maintain accurate and organized records of experiments, methodologies, and data analysis and support omics data management and integration into AbbVie’s workflow.

7.       Adhere to ethical guidelines and promote a culture of responsible research conduct. 

Bachelor’s Degree or equivalent education and typically 12 years of experience, Master’s Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience.

1.Effective communication and organization skills with the ability to support multiple projects, with a proven track-record to meet project milestones.

2.Proven experience in bioinformatics data, tools, and analysis, including proficiency in at least one programming language such as Python or R.

3.Hands-on experience with a range of omics-platforms ie. genomics, proteomics, and transcriptomics data analysis and data-integration.

4.Hands-on experience with human and/or animal tissue processing and single-cell preparation for genomics, proteomics, and transcriptomics data analysis.

5.Experience with molecular biology and biochemistry, in vitro culture functional assays, and the application of these techniques to pharmacological and molecular target validation studies.

6.Hands-on experience with animal handling and in vivo modeling will be a plus but not required.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

  • The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.

  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.

  • This job is eligible to participate in our short-term incentive programs. 

  • This job is eligible to participate in our long-term incentive programs. 

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community, and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.

Significant Work Activities: N/A

Travel: No

Job Type: Experienced

Schedule: Full-time


Minimum Salary $95,500

Maximum Salary $181,500

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