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AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

Principal Research Scientist I Senior Scientist II/Principal Scientist I – Eye Care Research - Retina

Irvine, California Req ID 2206843 Category Research and Development Division AbbVie

Senior Scientist II/Principal Scientist I – Eye Care Research - Retina

Description

The AbbVie Eye Care Research group is seeking an accomplished scientist with a broad scientific skillset to make substantial contributions to our retina disease research and discovery efforts to develop therapies for sight-threatening disease.  S/he/they will conceive of, execute, and communicate experiments for target identification/validation and discovery of novel therapeutics using a variety of in vitro and in vivo methodologies.  The successful candidate will leverage collaboration with internal and external stakeholders/experts to find answers to scientific questions and move projects forward.  They should be a highly motivated, hands-on experimentalist who is also capable of leading scientific projects. Emphasis is on the ability to successfully perform hands-on work, demonstrate scientific leadership skills, and interact in a team environment. Prior experience in fields of ophthalmology, retinal degeneration, or vision research is an asset, but not required.  In addition, the candidate should have a strong track record of cross-functional collaborations along with excellent oral and written communication skills.

Responsibilities

  • Designing and executing experiments to inform target biology using a variety of approaches to model disease processes, analyze signaling pathways, and evaluate structural and functional endpoints
  • Utilizing and developing in vitro and in vivo models of ocular disease for target validation and discovery of novel therapeutics
  • Identifying and validating pharmacodynamic readouts for novel targets
  • Generating high-quality experimental data to identify and confirm the mechanism of action of lead compounds, antibodies, and gene therapies identified through target discovery efforts
  • Presenting data and findings across various platforms, including project teams and extended research and discovery organization meetings
  • Using decision making, organization and communication skills to effectively collaborate with colleagues from cross-functional teams
  • Maintain an up-to-date understanding of new technologies and relevant scientific advances in support of our research goals
Qualifications:

Qualifications

  • PhD in biochemistry or cell biology, pharmacology, oncology, immunology, neurobiology, or a related field with 4+ years of relevant post-graduate work experience.
  • Drug development experience in a pharmaceutical or biotech industry setting is highly desired.
  • Expertise in gene therapy is desired.
  • Strong analytical skills and proficient at complex data analysis and interpretation
  • Must have strong communication skills and the ability to effectively communicate with both internal and external stakeholders, and to audiences of diverse backgrounds
  • Highly motivated, self-driven and results-oriented person, comfortable working independently in a fast-paced environment
  • Demonstrate high degree of flexibility in adapting to different projects and personalities as well as excellent networking and relationship-building skills (both internal and external)

 

**Equal Opportunity Employer Minorities/Women/Veterans/Disabled**

Significant Work Activities: Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel: No
Job Type: Experienced
Schedule: Full-time
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